A 40 year old male presented with fracture of femur. On 4th day he suddenly developed breathlessness, tachycardia and fever.
a. What is the probable diagnosis
b. Write on the pathogenesis of the condition
c. What are the special stains used for diagnosis
(Answer: Fat embolism) ( YSRUHS April 2024)
2. A 55years old lady was brought to the emergency room unconscious with history of road accident. She sustained multiple injuries, fractures of femur and tibia. These fractures are stabilized at surgery soon after admission. However 2 days after admission, she suddenly becomes dyspneic and developed tachypnoea and tachycardia, irritability, restlessness and it progressed to delirelium, coma and death on 7th day
What is the provisional diagnosis
Discuss the pathogenesis of the lesion
Describe microscopic picture of the lungs in the above condition
How frozen section of lung tissue help in final diagnosis at autopsy and mention various stains specific for it (Answer : Fat embolism and its consequences) (NTRUHS, March 2021)
4. A 55 years old lady was brought to the emergency room unconscious. her blood pressure was very low. pulse was weak and rapid. Her skin was warm and flushed. Her blood culture revealed growth of gram positive bacteria.
5. A 60 year old patient long history of rheumatoid arthritis presented with enlarged tongue and a history of diarrhoea. Urine shows positive heat test for proteins and ECG shows conduction disturbances.
a. What is the possible diagnosis and what will be ideal site for biopsy to confirm it
b. Name the lab technique for definite diagnosis
c. Write four types of this abnormal substance and their associated diseases
9. Define and describe the formation and pathogenesis of thrombus. Add a note on fate of the thrombus (RGUHS, July 2008, Jun 2011, Dec 2013)
10. Define thrombosis. Describe the etiopathogenesis, pathology and fate of thrombosis in detail (RGUHS- Jan 2009, Jun 2009,Dec 2013)
11. Define Embolism. Discuss different types of Emboli. (RGUHS- Dec 2011)
12. An young stout male met with an accident. He sustained multiple injuries, fractures of femur and tibia. These fractures are stabilized at surgery soon after admission. He is in a stable condition. However 2 days after admission he suddenly becomes dyspneic and developed tachypnea and tachycardia, irritability, restlessness and it progressed to delirium, coma and death on 7th day.
a. What is the provisional diagnosis
b. Discuss the pathogenesis of the lesion
c. Describe microscopic picture of the lungs in the above condition
d. How frozen sections of the lung tissue help in final diagnosis at autopsy and mention various stains specific for it.
(Answer : Fat embolism and its consequences)
SHORT QUESTIONS (4 MARKS)
Define thrombosis. Describe the virchows triad (YSRUHS, April 2024)
Differences between transudate and exudate(YSRUHS, April 2024)
Types of infarct (YSRUHS, April 2024)
Describe the morphology of different types of infarcts with examples (RGUHS Feb 2023)
Define infarct and enumerate the factors that determine the outcome of an infarct (NTRUHS, Dec 2022)
Explain briefly on Disseminated intravascular coagulation(NTRUHS, Feb 2022)
Pathogenesis of Septic shock ( SVIMS Oct 2021, NTRUHS Feb 2020)
Define and discuss the pathogenesis of edema (Pondicherry university June 2019)