Squamous cell carcinoma

Squamous cell carcinoma: Tissue lined by squamous epithelium with sheets of pleomorphic squamous epithelial cells infiltrating into the underlying fibrocollagenous stroma. Keratin pearls are seen in some foci (H&E,X50)

Squamous cell carcinoma: Sheets of pleomorphic squamous epithelial cells infiltrating into the underlying fibrocollagenous stroma. Keratin pearls are seen in some foci (H&E,X100)

Squamous cell carcinoma: Keratin pearl with adjacent pleomorphic squamous epithelial cells having round to oval vesicular nuclei with prominent nucleoli (H&E,X400)