Germ cell tumor – ovary

GERM CELL TUMORS – OVARY

• Germ cell tumors are composed of different tumor types derived from the primitive germ cells of the embryonic gonad

• Second largest group of ovarian neoplasms after the surface epithelial tumors

• Age: Infancy to old age, but seen more frequently from 1^st to 6^th

• In children and adolescents, 60% of tumors are germ cell tumors and 1/3^rd are malignant.

• In adults 95% of germ cell tumors are benign and contain mostly mature cystic teratomas

• Hypothetical model of histogenesis of germ cell tumors proposed by Teilum

Reference

• Aleksander Talerman, Russell Vang. Germ cell tumors of the ovary. In:Blausteins Pathology of the female genital tract by Robert J.Kurman, Lora Hedrick Ellenson, Brigitte M.Ronnett. Sixth edition. 847-908