Lesions in rheumatic valvulitis.

Lesions in Rheumatic valvulitis

• Valvulitis in acute Rheumatic fever is due to deposition of small fibrin vegetations along the lines of closure and by Aschoff bodies in the cusps

• In chronic Rheumatic fever, it is characterised by scarring, commissural adhesion, and stenosis and/regurgitation.

• Most common sequence of valves to be involved: Mitral (>90%)>Aortic>Tricuspid>Pulmonary valves

  • Characteristic FISHMOUTH or BUTTON HOLE stenosis seen

  • Vegetations called VERRUCAE overlying fibrinoid necrosis

  • Subendocardial MacCallum Plaques

  • Calcific aortic stenosis

 

References :

1. Robbins and Cotrans: Pathologic basis of diseases.8th edition

2. Harshmohan: Text book of Pathology.7th edition

By
Dr.B.Chaitanya (Consultant Pathologist, RDT hospital, Anantapur) (bchaitanya.med@gmail.com)