This tumor is associated with evidence of estrogen or androgen secretion or both
Gross- Unilateral, well circumscribed tumor
Cut section– Solid & white but may show areas of cyst formation, edema and foci yellow discolouration
Microscopy:
Pseudolobular pattern with cellular nodules separated by pauci cellular dense collagenous or edematous tissue
Within the nodules prominent thin walled ectatic vessels, varying degree of scleorsis and disorganised mixture of fibroblasts and round vacuolated cells, some of which have signet ring morphology are present. These clear cells contain lipid insteadof mucin which is seen in krukenberg tumor
Clear cells have eccentrically placed shrunken nuclei
Typical lutein cells may be seen in few cases
In rare tumor lutein cells may closely resemble luteinized thecoma
Rare tumors may have myxomatous areas
Immunohistochemistry: Tumor cells are reactive for inhibin and or calretinin
Differenial Diagnosis:
Fibroma
These tumors are homogenous appearance and lock pseudolobular patter
Krukunberg tumor
Tumor cells contain mucin instead of lipid as seen in sclerosing stromal tumor
Hemangiopericytoma
Though this tumor shows thin walled ecatatic vessels other cell morphology is lacking