LACTATING ADENOMA
- It’s a benign epithelial tumor composed of tubules lined by cells showing secretory change
- This tumor is usually detected during lactation and pregnancy
- It can also develop in the ectatic breast tissue which is found in areas like axilla, chest or vulva
- Grossly the tumor is well circumscribed mass
- Microscopically the lesion is well circumscribed composed of closely packed glands lined by cells having abundant eosinophilic cytoplasm.
- Hob nail pattern of cells and cells with cytoplasmic vacuolation may also be noted.
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Lactating adenoma showing lobules of closely packed glands (H&E,X50)
Lactating Adenoma: Dilated glands showing secretions in the lumen and cells showing cytoplasmic vacuolation (H&E,X100)
Glands lined by cells having cytoplasmic vacuolation and apical blebs (H&E,X100)
Lactating Adenoma: Glands lined by cells having cytoplasmic vacuolation and apical blebs (H&E,X400)
Lactating Adenoma: Hobnail pattern of epithelial cells (H&E,X400)
Lactating Adenoma: Epithelial cells having cytoplasmic vacuolation (H&E,X100)
Lactating Adenoma: Epithelial cells having abundant eosinophilic granular cytoplasm (H&E,X400)
