Clinical presentation – Solitary slow growing tumor or multiple lesions occur in Cowden’s syndrome.
Morphology:
It is typically lobulated with follicle centred proliferation of bland uniform polyhedral cells with clear glycogenated cytoplasm, surrounded by cuff of basement membrane material.
Tumor cells demonstrate peripheral nuclear palisading in lobules.
Lobules of cells often coalase producing a nodular mass in dermis.
Desmoplastic trichiemmoma is a type of trichilemmoma which shows pseudoinfiltrative margins initiated of pushing margins and have fusiform tumor cells with fibromyxoid change in the underlying stroma.